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KMID : 0043319990220040435
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Archives of Pharmacal Research
1999 Volume.22 No. 4 p.435 ~ p.436
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Total Synthesis of (±)-Homoepibatidine
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Kim Yong-Hyun
Won Do-Youn
Oh Chang-Young
Lee Kee-Young
Jeong Jin-Hyun
Jung Young-Hoon
Ham Won-Hun
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Abstract
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Total synthesis of ()-homoepibatidine (2), which contains the 8-azabicyclo[3.2.1] octane ring system, was achieved by using palladium-catalyzed Heck-type coupling reaction from 3.
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KEYWORD
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Alkaloids, Analgesics, Palladium, Stereocontrol
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